First Total Synthesis of Cucurbitaxanthin A Applying Regioselective Ring Opening of Tetrasubstituted Epoxides
نویسندگان
چکیده
منابع مشابه
Magnesium Oxide Nanoparticles for Catalytic Synthesis of 2-Substituted Alcohols from Regioselective Ring Opening of Epoxides in Water
Epoxides undergo regioselective ring opening with various nucleophiles using catalytic amount of nano magnesium oxide and water as solvent under mild reaction conditions. The remarkable features of this method are improved yields, high regioselectivity, and green chemistry agreement.
متن کاملmagnesium oxide nanoparticles for catalytic synthesis of 2-substituted alcohols from regioselective ring opening of epoxides in water
epoxides undergo regioselective ring opening with various nucleophiles using catalytic amount of nano magnesium oxide and water as solvent under mild reaction conditions. the remarkable features of this method are improved yields, high regioselectivity, and green chemistry agreement.
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New azanucleosides were obtained using sulphated zirconia (ZS) as catalyst in the nucleophilic oxirane ring opening reaction of 1-allyl-3-(oxiran-2-ylmethyl) pyrimidine-2,4(1H,3H)-dione and 1-allyl-5-methyl-3-(oxiran-2-ylmethyl)-pyrimidine-2,4(1H,3H)-dione, with (S)-prolinol. The new templates were obtained with good yields following a route which exploits the reactivity of epoxides in the pres...
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The regioselective opening of epoxides with organotin oxides 1 and 2, in presence of halogenated alcohols was developed, yielding the halohydrin derivatives. Introduction Epoxides are among the most versatile intermediates in organic chemistry due to the particular polarity and strength of their three member ring. Those characteristics make them in a very suitable substrate to the attack or man...
متن کاملNiobium Pentachloride Catalysed Ring Opening of Epoxides
Epoxide ring opening is a frequently required transformation in Organic Synthesis. In this paper we describe the application of NbCl5 for this purpose using three different substrates. Chlorohydrins, 1,2-diols, products containing solvent residues as well as rearrangement products are obtained, depending on both the substrate structure and reaction conditions. Rationalizations to account for so...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2004
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.52.780